Rat Anti-Mouse MERTK Antibody (S-R603)

Name: Rat Anti-Mouse MERTK Antibody (S-R603)S0B5157
Brand: Starter/斯達特
Price: 600 CNY
Availability: InStock

產(chǎn)品型號：S0B5157

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：136

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

MERTK, also known as MER proto-oncogene tyrosine kinase, is a receptor tyrosine kinase and a member of the TAM （TYRO3, AXL, MERTK） family. It plays crucial roles in various physiological processes, including cell survival, migration, differentiation, and the phagocytosis of apoptotic cells, a process known as efferocytosis. MERTK is expressed in multiple tissues, such as macrophages and retinal pigment epithelial cells, and is involved in regulating immune responses and maintaining tissue homeostasis. In the immune system, MERTK helps macrophages clear apoptotic cells and inhibits the innate immune response by activating STAT1, which induces the production of suppressors of cytokine signaling （SOCS1 and SOCS3）. Abnormal expression of MERTK has been linked to several diseases, including retinitis pigmentosa and certain cancers, making it a potential therapeutic target in cancer treatment.

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