Biotin Rat Anti-Mouse CD24 Antibody (S-R671)

Name: Biotin Rat Anti-Mouse CD24 Antibody (S-R671)S0B5143
Brand: Starter/斯達(dá)特
Price: 300 CNY
Availability: InStock

產(chǎn)品型號(hào)：S0B5143

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：112

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

CD24, also known as the heat-stable antigen （HSA） or small-cell lung carcinoma cluster 4 antigen, is a highly glycosylated protein anchored to the cell membrane via glycosylphosphatidylinositol （GPI）. It is a small mucin-like molecule expressed in various cell types, including B cells, immune cells, and tumor cells. CD24 acts as a "don't eat me" signal by interacting with Siglec-10 on macrophages, inhibiting phagocytosis and promoting immune evasion in cancer. This protein is overexpressed in many solid tumors, such as breast, lung, and colorectal cancers, and is associated with tumor progression and poor prognosis. Unlike CD47, CD24 is not expressed on red blood cells, making it a promising target for cancer immunotherapy without the risk of blood toxicity. Current research focuses on developing CD24-targeted therapies, including monoclonal antibodies and nanoparticle-based delivery systems, to enhance anti-tumor immunity.

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