Invivo anti-human CD32 (FcγRIIA) Recombinant mAb

Name: Invivo anti-human CD32 (FcγRIIA) Recombinant mAbS0B0689
Brand: Starter/斯達特
Price: 960 CNY
Availability: InStock

產(chǎn)品型號：S0B0689

更新時間：2025-10-10

廠商性質(zhì)：生產(chǎn)廠家

訪問量：240

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

FcγRIIA is a specific receptor for immunoglobulin G （IgG）, belonging to the family of Fcγ receptors （FcγR）. Among the FcγRs, FcγRIIA functions as an activating receptor. This receptor is primarily expressed on the membranes of immune cells, such as human platelets, and serves as a bridge between specific antibodies and effector cell functions, tightly linking humoral immunity with cellular immunity. FcγRIIA plays a crucial role in regulating IgG effects, as it can bind to monomeric and immune complex （IC） IgG. It can induce either activation or inhibition of functions, participating in driving antibody effector functions such as antibody-dependent cell-mediated cytotoxicity （ADCC） and/or antibody-dependent cellular phagocytosis （ADCP）, as well as antigen presentation and the release of chemokines and cytokines. In autoimmune inflammatory diseases like systemic lupus erythematosus （SLE）, the expression of FcγRIIA may exacerbate lupus nephritis and promote platelet activation.

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